Agriculture, Farm, and Pet Uses

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PROVEN SILVER TECHNOLOGY Agriculture Applications Unique Solutions for Ranchers and Farmers Background Information - Not for Public Dissemination Copyright 2024 WWW.CANADANANOSILVER.CA EMAIL--INFO@CANADANANOSILVER.CA

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SilverCeuticals uses a unique Nano-Silver particle that is... Triple-action (instead of just one) Outperforms other silvers that have up to 300 times the amount of silver Harmless to probiotic bacteria Continuous-action (keeps working and isn't used up) Made in the USA with lab-grade purified water (deionized water) and 99.99% pure silver NANO-SILVER PARTICLES

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The particles emit a resonant frequency between 890-910 tHz (UV range), so it can have an effect at a distance without needing direct contact. Finally, it contains an electrostatic charge which is essentially an electric field surrounding the particle. Our nano-silver particles are covered in thousands of Ag4O4 molecules that can steal up to 8 electrons, cycle them into its metallic core, and steal an additional 8 continuously. They are 'Continuous-Action' particles. Triple-Action Technology

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® TM Scours Research

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Rabbit Farming One Amish group was experiencing roughly a 25% loss rate of their rabbits during the weening stage. Delivery of the nano-silver to the rabbits through their water resulted in nearly a 0% loss rate. Scours in Cattle A farm with 30,000 head of dairy cattle and several thousand beef cattle is currently testing this nano-silver to address their frequent occurences of scours in the mothers and the calves. Horse Foals An Idaho assoc. experiencing scours in their horse foals was losing close to 25% of their foals, usually as the mare went back into estrus. Nano-silver was given to the foals, reportedly dropping the loss to 0. Nano-Silver in Application for Scours

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® TM Broiler Chickens

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Broiler Clostridium Pilot Study Comments on Project RW-23-2 Use of SilverCeuticals Nano Silver to Reduce/Prevent Necrotic Enteritis and/or to improve feed e ffi ciency. BACKGROUND: This Pilot Study was designed to test the use of 2 different dosage rates of SilverCeuticals Nano Sliver against the pathogen (Clostridium perfringens types A & C) known to cause Necrotic Enteritis in broiler chickens. Necrotic Enteritis is a major disease problem in the broiler industry and causes a decrease in feed consumption as well as severe depression, diarrhea, dehydration and death. These symptoms are due to the toxins produced by the bacteria causing severe ulceration of the small intestine which can lead to as much as a 50% death loss in affected flocks. This, in

turn, causes large economic losses for the industry as well as greatly reduces the number of birds available for food use in the marketplace. DATA ANALYSIS SUMMARY: My analysis of the data provided by CQR shows that at the 6oz/gallon dosage, there is a marked improvement in the feed efficiency (9.27%) in the treated vs non-treated group as well as a total prevention of illness, intestinal ulcers and death loss in the groups that were exposed to the CL. perfringens. In the challenged groups, treated vs non-treated, there was also an increased weight gain of 13.5%. At the 4 oz/gallon dosage there was some improvement in both feed efficiency and weight gain but not nearly as remarkable. There was also death loss and lesions at this rate. CONCLUSION AND

RECOMMENDATION: The data provided by this Pilot St shows that the use of SilverCeuticals Nano Silver can greatly reduce or eliminate the overgrowth of Cl. perfringens in the intestines of broiler chickens thus improving feed efficiency as well as increase the rate of growth. The numbers of birds placed in this trial are not statistically significant enough to base a final conclusion on and was only intended to give an indication of whether or not the product would have any affect at all. After seeing the data, I would recommend performing a larger, statistically valid study which will hopefully have similar results, thus, showing repeatability. Royce A Wilson DVM rawilsondvm@gmail.com

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TM Horse Lung Infections ®

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These lung infections can be evidenced by the exercise- induced bleeding from their nostrils. Veterinarians were reporting that daily nebulization of the race horses with our Nano-Silver Technology resulted in better breathing and faster run times. This is NOT a PED. Many race horses develop low-grade lung infections which affect their oxygen levels and their ability to run at full capacity. Lung Infections in Race Horses

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Nano-Silver Horse Nebulization This horse is being nebulized with our Nano-Silver Technology. Eighteen horse study white paper available upon request.

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Barrel Racing After completing a round of nebulization with our nano- silver technology, one horse shaved nearly a second off their normal race time. Improved Quality of Life When applied, this nano-silver can reduce the suffering and improve the output of these animals with simple, safe, and regular care. 100 Horses per Week Currently there are 100 race horses nebulized every week with our Nano-Silver Technology by Veterinarians to address these infections. Nano-Silver in Application

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TM Field and Surface Wash ®

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H O MOLECULE 2 2 A powerful combination of nano-silver and H2O2 that is... Non-toxic to people, plants, and animals Clear formula that is Non-Staining to turf fields and hard, non-porous surfaces Odor Free (No smell) Quick Kill Long-Lasting Efficacy Field Wash BENEFITS +

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USP-51 Facility Accreditation Analytical Resource Laboratory ISO/IEC 17025:2017 Accreditation: 77504 FDA Registration: 14214473726 ARL Laboratory Research Showed Full Efficacy in 5 Minutes Testing the field wash against MRSA, Ringworm, and the USP-51 Standard 5 organisms showed full kill by the first 5 minute checkpoint. 4 Week Preservation Upon completion of the 28 day test, the field wash maintained the full efficacy with no regrowth after the initial 5 minute kill.

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Dilution of 1/1000 At full strength the Field Wash was too potent and effective for them to test and get accurate readings. To make it work in their test, they had to dilute the Field Wash potency down one thousand times (1/1000). 10 Minute Efficacy Even diluted down to a 1/1000 potency, the Field Wash had greater than an 87.41% (0.9 logs) kill at 10 minutes and one hour. University Testing Facility This Field Wash was tested on Covid 19 by the Institute for Antiviral Research at USU to prove efficacy at 10 minutes and 1 hour. USU Covid 19 Research

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Boom Sprayer Application Using a boom sprayer, approximately 20-30 gallons of the field wash was applied to their practice turf fields. Lasts 5 Weeks The in-house field testing done by BYU showed that the product kept their turf fields free of microbes for 5 weeks before needing to be reapplied. Real World Application Brigham Young University did their own in-house testing directly applying the product to their turf fields. BYU Turf Field

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BYU Letter of Recommendation

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The Field Wash comes in: 55-gallon drums or 330-gallon totes Field and Surface Wash Containers

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Application Instructions

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Application Instructions Ctd.

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Facilities and Transportation Equipment Stadiums and Stadium Seating Agriculture and Golf Courses Locker Rooms, Restrooms, and stalls More Uses for this Unique Field Wash Technology...

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TM ADDITIONAL RESEARCH & COMBINED THERAPY ®

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Human Ingestion Safety Study Published human ingestion safety study on this unique silver technology showing no negative effect on any of the many tested body systems including... https://pubmed.ncbi.nlm.nih.gov/23811290/ Metabolic Hematologic Urinalysis Sputum Induction Chest MRI Abdomen MRI ...with no changes noted.

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Silver / Antibiotic Combination Study Published study on this unique silver technology showing synergistic or additive effect in 94 of 96 tests when combined with antibiotics https://www.jstor.org/stable/24094292 Bactericidal activity of combinations of Silver-Water Dispersion with 19 antibiotics against seven microbial strains 19 - Antibiotic Combinations 07 - Different Microbes 89 - Additive Outcomes 05 - Synergistic Outcomes The Nano-Silver Made Some of the Antibiotics as much as 10x more effective

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H5N1 Bird Flu Study Published H5N1 Study Highlights: https://lifesilver.com/facts/H5N1_Effect.pdf 100% Increase in Survival rate over control group Potential immunomodulatory effect in the animals Host weight increases during time of therapy Especially of interest was the observation that 60% of the infected mice treated with this compound survived compared to the 30% in the placebo- treated controls. Although not statistically significant because of the number which survived in the latter controls, this effect is strongly suggestive a disease-inhibitory effect may have occurred. At two time points during the SaO2 assays, days 3 and 6, the declines normally seen were significantly lessened (P<0.01), and there was a general lessening of decline

throughout the times of assay (Figure 1). Modest inhibition in lung scores were seen in this treated group as well, especially on day 6... Oral gavage treatment began 7 days prior to virus exposure and continued twice daily for a total of 17 days. Treatments with both formulations provided a suggested inhibitory and preventive effect on this virus infection as seen by either less animals dying in the treated groups than in the placebo-treated controls, delay in mean day to death, lessened SaO2 decline, modest inhibition of lung consolidation, and/or lessened virus titers in the lungs. Formulations were well tolerated by the toxicity control mice as seen by no deaths occurring in them and host weight increases observed during time of therapy... NIH

Bird Flu Study Excerpts on this Nano-SilverTechnology It is also possible that this material is exerting a mild immunomodulatory effect in the animals... the greatest immunologic effect is not necessarily at the highest dose used...

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JOURNAL OF WOUND CARE NORTH AMERICAN SUPPLEMENT, VOL 26, NO 4, APRIL 2017 100% Inhibition of both gram negative and positive pathogens Effective both on the dressing and in the wound tissue Total inhibition of biofilm formation Texas Tech Animal Wound Study Published Study Highlights On This Unique Nano-Silver Technology : The Ability of a Silver Gel Wound D ressing to Kill Bacteria In Vitro and In Vivo (Excerpts)

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TM WOUND USE EXAMPLES IN ANIMALS & HUMANS ®

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Horse Wound Case Study The cause was unknown. The horse was kept in an outdoor corral, and the owner thought it may have been caused by a cougar or possibly by another horse. A large flap of skin was missing from the wound and it was infected. The attending vet suggested that putting the horse down was probably the best option due to the infection, the wound's large surface area, and the inability to cover the wound due to its location. The owner, familiar with the nano-silver gel, opted to try and heal the wound first. The gel was applied once daily by the owner and left uncovered. No other wound healing products were used. The tissue regrew and the wound completely closed after about 6 months. The infection quickly subsided and did not reoccur. It

continued to heal to almost unnoticeable conditions, with both the skin and hair growing back, and almost no scar tissue formation. NANO-SILVER GEL

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Wound Healing Case Studies Infection Control In a Serious Third Degree Burn. Subject: 88 year old woman Wound: Third degree burn over both thighs with potential pseudomas aeruginosa, and MRSA infections. Treatment: Silver Sol gel sprayed on topically once a day when bandages were changed. Results: Photos illustrate total healing in 65 days. https://argasol.com/pdf/6.pdf Day One: Third Degree burn deep into the skin, adipose tissue and muscles. Subject was unable to receive skin grafts do to her age and compromized immunity. Day 65: Complete healing with no infection. The wound is discolored but relatively scar-free after 65 days.

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Background Method Results Face Burn Case Study 47 year old male, who is a practitioner, presents with significant deep partial thickness (2nd degree) burns to the hands, face, and neck from a gasoline fire. Upon evaluation at the Burn Center, the patient was told he would "likely never look the same again." Patient applied the SilverCeuticals™ Nano-Silver Gel topically 3-5 times daily to the affected areas. The Nano-Silver Gel was the exclusive treatment days 1-3 for his face. On days 4-6, he used the Nano-Silver Gel combined with other therapies while in the burn center, and days 7-14 he used primarily the Nano-Silver Gel. See pictures above. At a later follow-up with his burn doctors, the patient was told he would "likely not have any scarring at

all." SILVERCEUTICALS® NANO-SILVER GEL

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Hand Burn Case Study Hand Burn Case Study Case study on the healing potential of this silver technology for burn treatment, published by Springer in the textbook 'Wound Healing Research - Current Trends and Future Directions' 2021. https://link.springer.com/chapter/10.1007/978-981-16-2677-7_12 "A 1.5-year-old female child burnt her hand on a stove burner. The patient was hospitalized for 3 days and treated by a physician for severe second degree burns." After being discharged from the hospital, a silver hydrogel (24ppm) was used topically whenever the dressings were changed. At the physicians direction, the product was switched to a higher strength silver hydrogel (32ppm) around day 17. "The wounds were healed completely by day 105" "Skin grafts were

suggested by the physician but were put on hold."

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Ringworm Case Study Case study on the healing potential of this silver technology on ringworm, published by Springer in the textbook 'Wound Healing Research - Current Trends and Future Directions' 2021. https://link.springer.com/chapter/10.1007/978-981-16-2677-7_12 "A10-year-old female suffering from ringworm infection with inflamed and painful skin" The infection was "completely cured by day 10." She was treated with a silver hydrogel (24ppm) local application twice a day and the affected area was left uncovered.